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4 Types of Dose Finding Studies Used in Phase II Clinical Trials

doses-1One of the key goals of phase II is to determine the optimal dose that you will use going into your phase III trials and ultimately will be used on your product label submitted for approval as part of the new drug application (NDA). An optimal dose is a dose that is high enough to demonstrate efficacy in the target population, yet low enough to minimize safety concerns and adverse events.

This article examines four common study designs used to determine the optimal dose.